Biological markers
Coordinator: Dr Guillaume Grzych (CHU Lille)
The interest of a working group dedicated to biological markers of nitrous oxide consumption and abuse lies in the importance of developing reliable diagnostic tools to detect exposure and abuse of this substance.
Nitrous oxide, although often used recreationally, presents significant health risks, and early detection of its misuse can prevent serious consequences.
The main tasks of this working group are manifold:
Conduct in-depth research to identify and validate specific biomarkers of nitrous oxide consumption and abuse.
These markers may include biochemical, genetic or metabolic changes detectable in body fluids such as blood, urine or saliva.
Develop standardized, sensitive diagnostic tests based on identified biological markers.
These tests will enable rapid, accurate detection of nitrous oxide exposure, facilitating diagnosis and early treatment of at-risk users.
Train healthcare professionals to use new diagnostic tests and interpret results.
Make these professionals aware of the clinical implications of biological markers and the importance of early detection of nitrous oxide abuse.
Develop clinical guidelines for integrating biomarker testing into care protocols.
These guidelines will include recommendations for the follow-up and treatment of patients with positive results.
Encourage collaboration between different specialists, including toxicologists, biochemists, physicians and public health researchers, for a multidisciplinary approach to managing nitrous oxide abuse.
This collaboration aims to optimize screening strategies and improve patient outcomes.
Study the long-term consequences of nitrous oxide exposure, using biological markers to assess chronic health effects. This research will contribute to a better understanding of the associated risks and the development of preventive measures.
By fulfilling these missions, the working group will make a significant contribution to improving patient care, reducing the risks associated with nitrous oxide consumption, and promoting safer, better-informed public health.
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