The IMPECS (Impact de l'environnement chimique sur la santé) research unit is a multi-disciplinary team whose aim is to gain a better understanding of the reaction complexity of lung tissue exposed to chemical compounds in the air we breathe, to explain inequalities between individuals with regard to these substances, to gain a better understanding of risk levels and, consequently, to better prevent risks and limit the impact of this environment on respiratory health. Our research unit brings together toxicologists, epidemiologists, physicians and pharmacists, divided into two research areas:
Axis 1: Mechanisms of toxic action of air contaminants: In vivo and in vitro experimental approaches to analyze the pneumotoxicity of air contaminants and identify biomarkers of effect.
Axe 2 : Biosurveillance humaine : Recherche et validation chez l’Homme de biomarqueurs d’exposition, d’imprégnation et d’effets précoces des aérocontaminants.
Le groupe de métabolomique clinique (CliMe) de l’Université de Liège résulte d’une collaboration stratégique entre le Département de Chimie Clinique du CHU et de l’Université de Liège et le Groupe de Métabolomique du Centre Interdisciplinaire de Recherche sur le Médicament (CIRM) de l’Université de Liège. Répondant à une demande accrue pour des analyses métabolomiques avancées, CliMe fusionne la recherche clinique et préclinique avec la pratique médicale quotidienne.
Drawing on the expertise of the Clinical Chemistry Laboratory in biomarker validation and mass spectrometry, as well as the competence of CIRM's Metabolomics Group in NMR, CliMe is committed to being at the heart of innovation for precise, personalized medicine. This interdisciplinary team boasts a state-of-the-art analytical platform, equipped with high-resolution mass spectrometers and sophisticated NMR systems, backed by in-depth expertise in biological sample preparation and metabolomics data analysis.
